DIFFERENCES PLATELET INDICES IN HYPOPROLIFERATIVE AND HYPERDESTRUCTIVE THROMBOCYTOPENIA

Thrombocytopenia can increase the risk of bleeding. Determination type thrombocytopenia is important because it will affect patients treatment. The gold standard for distinguishing types bone marrow examination. This examination invasive and carries Platelet indices are simple less reliable in thrombocytopenia. aim this study to evaluate value platelet differentiating thrombocytopenia.This used retrospective cross sectional study. Subjects with leukemia, aplastic anemia, MDS hypoproliferative (group 1), dengue fever, ITP, Evans syndrome, sepsis, pneumonia, typhoid fever hyperdestructive 2). Inclusion criteria were subjects data a count <100,000 name, age, sex, diagnosis count, PCT, MPV, PDW. Group 1 consisted 103/150 (68.67%) group 2 47/150 31.33%) subjects. vs 2, MPV 10,02  0,85 11,72 1,11 (p = 0,017) PDW 10,0 (7 – 15,70) 14,5 (10,40 19,40) <0,001) dan PCT 0,04 (0,01 0,19) 0.06 0,10) 0,208) Thrombocyte 41 (11-97) 50 (8-90) 0,380). values higher thrombocytopenia, there was no thrombopoiesis abnormality produce young platelets. difference not significant significantly different little significant. differentiate